TNM 7 Classification





TNM 6 Classification



1. Rules for Classification




The classification applies only to primary carcinomas of the vulva. There should be histological confirmation of the disease.



A carcinoma of the vulva that has extended to the vagina is classified as carcinoma of the vulva.



The following are the procedures for assessing T, N, and M categories:



T categories. Physical examination, endoscopy, and imaging

N categories. Physical examination and imaging

M categories. Physical examination and imaging



The FIGO stages are based on surgical staging. (TNM stages are based on clinical and/or pathological classification.)



2. Regional Lymph Nodes


The regional lymph nodes are the femoral and inguinal nodes.



3. TNM Clinical Classification


3.1. T - Primary Tumour



TX. Primary tumour cannot be assessed

T0. No evidence of primary tumour

Tis. Carcinoma in situ (preinvasive carcinoma)

T1. Tumour confined to vulva or vulva and perineum, 2 cm or less in greatest dimension

T1a. Tumour confined to vulva or vulva and perineum, 2 cm or less in greatest dimension and with stromal invasion no greater than 1 mm*

T1b. Tumour confined to vulva or vulva and perineum, 2 cm or less in greatest dimension and with stromal invasion greater than 1 mm*

T2. Tumour confined to vulva or vulva and perineum, more than 2 cm in greatest dimension

T3. Tumour invades any of the following: lower urethra, vagina, anus

T4. Tumour invades any of the following: bladder mucosa, rectal mucosa, upper urethra; or is fixed to pubic bone



3.2. N - Regional Lymph Nodes



NX. Regional lymph nodes cannot be assessed

N0. No regional lymph node metastasis

N1. Unilateral regional lymph node metastasis

N2. Bilateral regional lymph node metastasis



3.3. M - Distant Metastasis



MX. Distant metastasis cannot be assessed

M0. No distant metastasis

M1. Distant metastasis (including pelvic lymph node metastasis)



4. pTNM Pathological Classification


The pT, pN, and pM categories correspond to the T, N, and M categories.



pN0. Histological examination of an inguinal lymphadenectomy specimen will ordinarily include 6 or more lymph nodes. If the lymph nodes are negative, but the number ordinarily examined is not met, classify as pN0.



5. G Histopathological Grading


See definitions on .



6. Stage Grouping







































































Stage 0
Tis
N0
M0
Stage I
T1
N0
M0
Stage IA
T1a
N0
M0
Stage IB
T1b
N0
M0
Stage II
T2
N0
M0
Stage III
T1. T2
N1
M0
T3
N0. N1
M0
Stage IVA
T1. T2. T3
N2
M0
T4
Any N
M0
Stage IVB
Any T
Any N
M1





7. Summary



























































TNM
Vulva
FIGO
T1
Confined to vulva/perineum ≤2 cm
I
T1a
Stromal invasion ≤1.0 mm
IA
T1b
Stromal invasion >1.0 mm
IB
T2
Confined to vulva/perineum >2 cm
II
T3
Lower urethra/vagina/anus
III
T4
Bladder mucosa/rectal mucosa/upper urethra/bone
IVA
N1
Unilateral
III
N2
Bilateral
IVA
M1
Distant metastasis
IVB